nrf2 glutathione molecular hydrogen New insights into crosstalk between pathway and ferroptosis in lung disease Stimulation of de novo glutathione Regulation of the Nrf2 pathway

& Mohammed, A

APD is more likely to occur in women of reproductive age, especially those with a history of other autoimmune or allergic conditions

4.1 Clinical relevance of the CLP model The CLP model was selected for its unique ability to recapitulate core clinical features of SAE: polymicrobial sepsis, hippocampal neurodegeneration, and chronic cognitive impairment ( 4.2 Microglia-mediated oxidative neuronal injury Microglial activation initiates neuronal damage, and a previous study revealed that the microglial inhibitor minocycline reduces neuronal apoptosis ( in vivo oxidative stress ( Mechanistically, a microglial inflammation-oxidative stress feedforward loop perpetuates injury: Activated microglia secrete neurotoxins, impairing neuronal mitochondrial function and antioxidant capacity (such as GPX4), thus increasing ROS leakage

En clinique ou en tlmdecine, partout au Qubec